Category: urethra

Chemical Structure

Viagra Soft, specifically Sildenafil Citrate 100 mg, has a distinct chemical composition. Its structure includes a pyrazolopyrimidinone core, characterized by a triazole-piperazine moiety. The molecular formula is C22H30N6O4S. This compound is primarily recognized for its selective inhibition of phosphodiesterase type 5 (PDE5). Its molecular interactions involve cyclic guanosine monophosphate (cGMP) in smooth muscle cells. The crystallographic data provide a glimpse into its stereochemical configuration. This structural formation plays a key role in its pharmacokinetics and biological efficacy.

Mechanism of Action

Sildenafil Citrate 100 mg operates by targeting PDE5. It enhances the effect of nitric oxide (NO) by inhibiting PDE5, which is responsible for cGMP degradation in the corpus cavernosum. With PDE5 inhibited, cGMP levels increase, resulting in smooth muscle relaxation and increased blood flow. This action is crucial for achieving and maintaining an erection in response to sexual stimulation. Its efficacy is noted in individuals with erectile dysfunction (ED), improving erectile response. The drug’s pharmacodynamics showcase its potential in treating ED effectively.

Who Can Not Take Viagra Soft

Individuals with certain medical conditions should avoid Sildenafil Citrate 100 mg. Those with a known allergy to sildenafil or any component of the tablet must refrain. Patients on nitrates or guanylate cyclase stimulators must not use it due to potential severe hypotension. Individuals with recent stroke or myocardial infarction history are advised against its use. Severe hepatic impairment and certain retinal disorders are also contraindications. These restrictions underscore the importance of a tailored medical approach before administration. Consulting a healthcare professional is crucial for risk assessment.

Viagra Soft Cautions

Using Sildenafil Citrate 100 mg demands caution. It may interact with other medications, influencing its efficacy and safety. Grapefruit products can alter its metabolism, potentially enhancing adverse effects. Monitoring for sudden vision loss is vital, as non-arteritic anterior ischemic optic neuropathy (NAION) is a rare side effect. Patients must be aware of potential priapism, a prolonged erection that requires immediate medical attention. Those with cardiovascular risk factors should exercise caution. A thorough medical evaluation aids in balancing benefits with potential risks.

Viagra Soft Toxicity

Sildenafil Citrate 100 mg toxicity relates to excessive dosing. Overdosage may amplify its adverse effects, leading to headaches, dizziness, and dyspepsia. Cardiovascular disturbances, including tachycardia and palpitations, are possible. In severe cases, seizures and syncope could occur. The therapeutic window is narrow, emphasizing adherence to prescribed dosages. Laboratory studies and clinical trials indicate a need for vigilance in dose adjustments. The drug’s safety profile necessitates professional supervision.

Is Non-Prescription Viagra Soft Available?

Sildenafil Citrate 100 mg is not available without a prescription. This requirement stems from its potential interactions and contraindications. Regulatory bodies mandate prescriptions to ensure patient safety. Self-medication poses significant risks due to complex interactions with other drugs and underlying health conditions. Healthcare provider consultation is essential for obtaining and using it safely. The absence of an over-the-counter option underlines the significance of professional guidance.

For more detailed scientific insights, visit NCBI.